ONCOLOGY MCQs WITH ANSWERS & EXPLANATIONS

ONCOLOGY MCQs WITH ANSWERS & EXPLANATIONS

SET BY: SULEIMAN NDORO JNR (DR AUDI)

1. Cancer antigen 125 (CA-125) is the most sensitive in which of the following cancers?
A. Ovarian epithelial cancer
B. Breast cancer
C. Lung cancer
D. Gastrointestinal cancer

2. Human chorionic gonadotrophin (HCG) is most specific for:

A. Hydatidiform moles
B. Seminoma
C. Choriocarcinoma
D. Ovarian non-seminatous germ cell tumors

3. Which of the following statements is false about Prostate-Specific Antigen (PSA)?
A. It is a serine protease

B. It is a glycoprotein member of human kallikrein gene family
C. It is always elevated in 95% of prostate cancer
D. It liquefies semen in excretory ducts of prostate

4. In breast cancer screening, mammography is done________

A. Every 5years starting at age 40
B. Every 3 years between age 20 and 39
C. Yearly, starting at age 40
D. Every 1 to 3 years between age 18 and 40

5. In prostate cancer screening, PSA is done __________

A. Yearly after age 65
B. Yearly after age 60
C. Yearly after 40
D. Yearly after age 50

ANSWERS

1. A. Ovarian epithelial cancer
The correct answer is A: In descending order: Ovarian epithelial cancer (75%), Gastrointestinal cancer (10%), Lung cancer (5%) and breast cancer (5%)

2. B. Seminoma

3. C. It is always elevated in 95% of prostate cancer
The correct answer is C: PSA can be elevated in BPH and prostatitis

4. C. Yearly, starting at age 40
The correct answer is C: In breast cancer screening, breast self-examination is done monthly after age 20. Breast physical examination is done every 3 years between ages 20 and 39, then yearly. Mammography is done yearly, starting at age 40.

5. D. Yearly after age 50

The correct answer is D: In prostate cancer screening, rectal examination and blood test for PSA is done yearly after age 50 or age 45 if in a high-risk group.