PAEDEATRICS CASE QUESTION
SET & COMPILED BY: SULEIMAN NDORO JNR (DR AUDI)
Audi is a one year old boy from Ukunda who is brought by her
mother to your clinic due to swollen testicles. He has also had high body temperatures and
general body malaise and his appetite has been diminishing for the past one month.
He is pale and has high fevers on examination and ecchymosis on his skin.
His complete blood count results reveal pancytopenia.
a)
What could be the possible condition?
b)
List the types of Audi’s condition above.
c)
Outline the etiology of Audi’s condition
d)
List the investigations that can be done
e)
List the 2 main ways of treating Audi
f)
Name ten complications of Audi’s therapy
ANSWERS
a)
Leukemia
b)
–Acute lymphoblastic leukemia (ALL)
-Acute myeloid leukemia (AML)
-Chronic myeloid leukemia (CML)
-Chronic lymphoblastic leukemia (CLL)
c)
–Genetic factors-chromosomal translocations and
associations with certain genetic condition
-Environmental factors-ionizing radiation
and certain chemicals e.g. benzene
-Early infant infections
d)
–Peripheral blood film
-Bone marrow aspiration and biopsy – gives definitive
diagnosis
-Imaging- to determine the extent of the
disease
-Cerebrospinal fluid (CSF) analysis- to
detect CNS involvement
e)
–Chemotherapy
-Bone marrow transplant
f)
–Tumor lysis syndrome
-Renal or hepatic impairment
-Thromboembolism
-Immunosuppression
-Alopecia
-Obesity
-Congestive cardiac failure
-Cognitive impairment
-Psychosocial impairment
-Second malignancy
How does leukimia affect testicles to swell?
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